AS4™

Astragaloside IV (AS-IV) primarily works by activating the enzyme telomerase, which in turn helps to prevent telomeres from shortening and can even lead to their elongation, thus supporting cellular health and potentially delaying aging. It activates telomerase by increasing the expression of the TERT gene (which codes for telomerase) and by influencing signaling pathways like Src/MEK/ERK, ultimately counteracting telomere attrition.

Telomeres are protective, repetitive DNA caps at the ends of chromosomes, similar to plastic tips on shoelaces, that prevent genetic data from unraveling during cell division. As cells divide, these caps shorten, acting as a biological clock for aging; critically short telomeres lead to cell death or senescence.

Telomerase is a specialized ribonucleoprotein polymerase enzyme that maintains telomere length by adding DNA (TTAGGG repeats) to the ends of chromosomes. It acts as a reverse transcriptase to counteract the natural shortening of chromosomes during cell division, allowing cells to bypass senescence and continue dividing.

Astragaloside IV (AS-IV) is a natural, bioactive saponin compound derived from the Astragalus membranaceus plant. AS-IV acts as a telomerase activator, which helps prevent telomere shortening and extends cellular lifespan. AS-IV works by activating the Src/MEK/ERK signaling pathway, which subsequently upregulates telomerase reverse transcriptase (TERT) expression.

Standardized Astragaloside IV (AS-IV) is critical, as the primary active compound in Astragalus membranaceus, it ensures consistent potency, quality, and therapeutic efficacy. Standardization guarantees that each dose contains a specific amount of AS-IV, allowing for reliable results, as research indicates AS-IV has a dose-dependent effect.

Quality assurance: It prevents variability that can occur between different plant batches, ensuring the supplement actually contains the active compound at an effective concentration.

Standardizing AS-IV ensures that AS4™ is a “therapeutic agent” rather than an inconsistent herbal extract.

AS4™

$90

Normally priced at $120

SLOW

Shortening of

Telomeres

  • AS4™ Telomerase Support Formula

  • Standardized Astragalus Extract (10% Astragaloside IV)

  • 60 Capsules per Bottle

  • Designed to Support Healthy Cellular Aging

    Apply code JUSTICE upon checkout get AS4 at $90